My Malignant Melanoma

I see someone is promoting a dietary supplement called Biovitali Vitalcells on the What Now board with what looks to the unsophisticated eye like some reasonable scientific evidence. I guess the moderators will eventually get round to deleting this, but wouldn't it be better to have a look at how strong the evidence is?

So let's have a look at that evidence, which is:

1. The product has apparently been patented

2. It is supposedly endorsed by the MD Anderson Cancer Research Centre and the National Foundation for Cancer Research

3. Laboratory trials show it not just to stop cancer and cardiovascular illnesses in their tracks, but to prevent them occurring in the first place, and to extend life by 30%

Taking these claims one by one-

1. Patenting something does not mean that anyone has shown it to actually work. It is a commercial device to prevent anyone copying your work. Having a patent does not mean that something does what it claims. This is no evidence at all.

2. It seems not to be endorsed by either the MD Anderson Cancer Research Centre, or the National Foundation for Cancer Research as is claimed in the manufacturers literature. Both of the organisations in fact have advice against cancer patients and others taking non-prescribed food supplements on their websites, here and here. Neither of their websites make any mention of this product.

3. If the non-peer-reviewed in-house research on the manufacturer's website were true, and applicable to humans, cancer would be no more serious than the common cold. Every single one of the ingredients shows at least 80% tumour inhibition, and together they are even more powerful. But every one of these ingredients is a substance present in normal foodstuffs. How can this be?

Let's see what might be going on. Have a look at the table at the end on lifespan increase. 100% of these mice get cancer during their lives. That is because this strain of mouse has been specially bred to get skin cancer.

The experimenters made getting cancer a racing certainty in their antioxidant experiments by also injecting the mice with a powerful cancer-causing agent, and then constantly feeding them with something which helps cancer to grow.

They have not published their experimental protocol, but let us generously assume it was similar to that used in this real scientific research, despite us not being in a position to check whether they did things properly.

They fed the supplements along with the substance which helps cancer to grow, so that exposure to the promoter and the antioxidants was simultaneous.

Every single one of the ingredients showed incredible levels of tumour inhibition, far higher than that shown by the real treatment linked to previously. If I were a mouse genetically engineered to get a type of skin cancer who happened to have accidentally been injected with a potent carcinogen, and to be unfortunate enough to be on a drip of a drug which promoted the growth of cancer, it seems like this product would be well worth a look. Any other species, any other sort of cancer? Well, we'd have to look at the peer reviewed evidence.

Of course, this product is just a vitamin and antioxidant supplement, which contains the usual stuff, including a number of substances that in real people have been shown promote cancer when taken as a supplement, rather than inhibiting it, such as:

Beta Carotene
Vitamin A
Vitamin E
Vitamin C

Furthermore, the claims that taking combinations of these substances improved their effect is the opposite of what has been found in real studies. Combining beta carotene with vitamin A or vitamin E actually kills more people than either ingredient alone. Source.

There is therefore no chance whatever that the lab results shown in its website have any meaning for cancer patients.

Cancer Research UK advise as follows about all food supplements:

" We need a lot more research in this area before we will know for sure which vitamin and diet supplements may play a role in helping treat, prevent or control cancer. The best way to get the vitamins and minerals you need is through a balanced and varied diet, with plenty of fruit and vegetables. Vitamin supplements don’t have the same benefits as naturally occurring vitamins in fruit and vegetables."

And of course we now know that for those receiving active treatment, antioxidants and vitamin C can block the effects of chemotherapy and radiotherapy. Source.

Someone has suggested on the What Now site that explaining all of the above is unnecessary, and that the last thing the site needs are know-alls telling you all what to think. But here is that same person thanking me for educating them on this very subject after they gave bad advice to someone.

Maybe the site doesn't need know-alls, but know-somethings are useful in situations like this, aren't they? Failing that, the know-nothings could at least not give advice to desperate people in areas they know nothing about.

I see someone has started a new "natural treatment" thread on WN. I'll be interested to see if Gary's polite and sound advice is well-taken. History suggests no, but the site is under moderator lockdown whilst my complaint is being investigated, so who knows?

Labels: Biovitali, Cancer, Clinical, Diet, evidence, immune system, Malignant, Medicine, Melanoma, Nature, promotion, quack, Supplements, Trial, Vitalcells, Vitamin D, Vitamins

There's been some posting recently on Cancerbacup's message boards about Vitamin D and cancer prevention.

Whilst this is not as ridiculous as all other claims for megavitamin therapy, the evidence is presently inconclusive as far as Cancer Research UK and the NHS are concerned:

CRUK
NHS

The poster on the subject also failed to understand that the study showing poor prognosis associated with low vitamin D levels did not prove that low vitamin D was responsible for poor prognosis. It showed that one followed the other, but day does not cause night. It is false reasoning to say that if something follows something else, the first necessarily caused the second.

In any case, as ever, prevention is not cure. Even if a higher RDA for vitamin D did have beneficial effects on the incidence of some cancers, that's a bit late for those of us already diagnosed, and recommending sunbathing to melanoma patients would be highly contentious.

Labels: Cancer, Malignant, Melanoma, Supplements, Vitamin D, Vitamins

Thought I'd crosspost this from a discussion we have been having on the cancerbacup forum:

"Essiac and Laetrile are useless against cancer. Laetrile gives those who take it cyanide poisoning, though whether they notice the symptoms or not might depend on the dose, and personal susceptibility.

This view is supported by the following reputable organisations, who in turn have these opinions because scientists have tested the agents and found them not to work:

Cancer Research UK

US National Cancer Institute

Cochrane Collaboration

Note that these references should not be believed simply because the organisations publishing them are mainstream. That would be to fall for the same logical fallacy as quack medicine promoters, the "argument from authority". Someone is not right because they have an impressive title, or were nominated for, or even won the Nobel prize. Check out the research backing the claims.

Linus Pauling, (double Nobel Prize winner) for example was a genius in his field, but dead wrong about the effectiveness of Vitamin C against cancer.

Here is a summary of all scientific evidence to date on Laetrile as of June last year.

An interesting article on Laetrile by a doctor, and fully backed by scientific research appears here

To summarise the research listed above, Laetrile is ineffective aginst cancer, and basically has an identical effect to cyanide. Any replies to this post which do not back claims to the contrary with research from peer reviewed scientific literature as I have will be ignored.

As the very first post in the thread says: if I am taking both chemo and Mrs Caisse's tea, who cares which cured me? And indeed who can really tell if it was one, the other, or neither?

That I took essiac or whatever and my cancer got better no more shows that it cures cancer than day causes night. Sometimes cancer just gets better. Our bodies mount a successful last-ditch defence. Just because something follows something else, does not show the first thing caused the second. Only by trying a single agent many times under controlled conditions can we see whether it works or not.

Whilst we are in education mode, we can have a look at the claims made by other posters on this thread which are contradicted by the references I have given above. You can ignore this bit if you like, point by point rebuttals are tiresome to many people:

1. "It may be that B17 is a good one to go for, as the US have banned it." Laetrile is not a vitamin. It is a poison with no effect on cancer progression. It has been banned in the US because of this. This makes it a bad "one to go for".

2. "ordinary processed sugar will kill you long before the cyanide in apricot seeds will." The cyanide produced by laetrile is the same cyanide which is in Zyklon B. There isn't some sort of natural cyanide which is good for you.

3. "The "cyanide content" of almonds, is only released on contact with the cancer cell with which it reacts, and it is not activated in any other situation." In fact the cyanide is released on contact with all parts of the body, especially the digestive system, which is why oral administration is so much more acutely harmful. There is no scientific evidence of any specificity to cancer cells as claimed.

4. "In 1950 after many years of research, a dedicated biochemist by the name of Dr. Ernst T. Krebs, Jr., isolated a new vitamin that he numbered B17 and called 'Laetrile'." Laetrile has been known since 1830. Mr Krebs was not a doctor or a biochemist at all. His father was a doctor, but he was a simple snake-oil merchant. His father the doctor was a quack too. Harold Shipman was a doctor too. Being a doctor isn't an automatic guarantee of probity. Claiming to be a doctor when you are not is however pretty much a guarantee of quackery.

Some other fallacies:

1. "How can an apricot seed, provided by nature, be called a drug" The same way as opium provided by nature might, but I'm not calling it a drug, I'm calling it a poison. The most potent poison in the world, Botulinum toxin is a natural substances.

2. "Dr Budwig was nominated for a Nobel Prize SEVEN times" I could say the same thing of myself and no-one could argue. The committee does not publicise the names of nominees.

I will ignore the meaningless waffle, paranoid hysteria (international criminal conspiracies, please spare us!) and rudeness of the posters promoting quackery. I understand that some people's beliefs are not going to be changed by any amount of rational evidence, and they then resort to bullying tactics.

My opinions are not however beliefs of this nature. Show me a valid clinical trial of these agents which shows that they work, and I will change them. They are opinions backed by solid evidence. The other posters promote irrational beliefs which are flatly contradicted by the same evidence.

So it isn't a question of respecting others, or their beliefs. It a question of not allowing others to promote their dangerous and irrational beliefs with outright lies.

I don't know the other posters from Adam or Eve. I have nothing against them. Their ideas are however dangerous nonsense, founded only on the lies of commercially interested quacks and need to be countered with facts.

I will do this as many times as it takes, but I cannot see how they can come back with anything other than more irrational nonsense. Their claims have no basis in fact, as this post now demonstrates in detail (but only of course to anyone unwilling to believe in a global conspiracy to deny us effective anti-cancer agents by subverting the whole activity of science and medicine)"

Anyone hoping that I will publish comments on this post which amount to testimonials in favour of quackery are going to be disappointed, I'm afraid. We are not in the business of publishing unproven claims which could mislead vulnerable people here. Testimonials are vastly inferior evidence to the scientific studies I have linked to above. Publishing them might make it seem to the vulnerable that there are two sides to this argument, when there are not.

Labels: Alternative, Budwig, Clinical, Diet, Essiac, Forum, Laetrile, Malignant, Medicine, Melanoma, Resources, Trial, UK, Vitamins

I've just been over to the US Melanoma Patients Information Page to publicise the site. Whilst the main site has much good and fairly up-to-date information, I would never send anyone to the bulletin board, as there is a lot of unchallenged mumbo-jumbo on there.

I was particularly disgusted to see communications from the Gerson Institute, and the contact address of their staff on the BB, along with testimonials from the poor mugs they have cheated for their worthless "treatment". Gerson Treatment has no proven effect on MM, even if we are willing accept the clinic's own data.

I also saw much discussion of worthless, and in some cases harmful supplements and vitamins. Patients who had taken them were acting as if they were experts, making claims that they knew the precise temperature at which the enzymes in noni juice which cure cancer were deactivated, when no-one has ever shown that these enzymes exist, or that they affect cancer.

It isn't my job to regulate MPIP, but until they regulate themselves, the bulletin board is a very dangerous place for anyone not possessed of the facts about these alternative approaches.

S

Labels: Alternative, Gerson, Malignant, Medicine, Melanoma, MPIP, Supplements, Vitamins